Prof. Dr. Vahid Sandoghdar

Chair of Experimental Physics

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Email: vahid.sandoghdar@fau.de

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Publications

Paolini L., Romano M., Mangolini V., Tassoni S., Jiang S., Mazzoldi EL., Musicò A., Zendrini A., Kashkanova A., Sandoghdar V., Berardi AC., Giliani SC., Bergese P., Radeghieri A.:
Red blood cell-derived extracellular vesicles as biomaterials: the opportunity of freezing-induced accelerated aging
In: Biomaterials Science 14 (2026), p. 122-139
ISSN: 2047-4830
DOI: 10.1039/d5bm01349f

Brunner CM., Pietsch L., vom Sondern I., Röhrl M., Popov CR., Trollmann M., Taylor RW., Blessing M., Holler C., Almahayni K., Jaeschke SO., Sandoghdar V., Böckmann R., Lindhorst TK., Möckl L.:
Bottom-up Investigation of Spatiotemporal Glycocalyx Dynamics with Interferometric Scattering Microscopy
In: Journal of the American Chemical Society 147 (2025), p. 32799-32808
ISSN: 0002-7863
DOI: 10.1021/jacs.5c08659
Ginsberg NS., Hsieh CL., Kukura P., Piliarik M., Sandoghdar V.:
Interferometric scattering microscopy
In: Nature Reviews Methods Primers 5 (2025), Article No.: 23
ISSN: 2662-8449
DOI: 10.1038/s43586-025-00391-1
Luo S., Hebenstreit T., Shkarin A., Utikal T., Renger J., Sandoghdar V., Götzinger S.:
Highly Efficient Organic Single-Photon Source Operating at Cryogenic Temperatures
2025 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2025 (Munich, DEU, 23. June 2025 - 27. June 2025)
In: 2025 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2025 2025
DOI: 10.1109/CLEO/EUROPE-EQEC65582.2025.11109484
Mazal H., Wieser FF., Bollschweiler D., Sandoghdar V.:
Cryogenic light microscopy of vitrified samples with angstrom precision
In: Proceedings of the National Academy of Sciences of the United States of America 122 (2025), p. e2513583122
ISSN: 0027-8424
DOI: 10.1073/pnas.2513583122
Mazal H., Wieser FF., Bollschweiler D., Schambony A., Sandoghdar V.:
Cryo–light microscopy with angstrom precision deciphers structural conformations of PIEZO1 in its native state
In: Science Advances 11 (2025), Article No.: eadw4402
ISSN: 2375-2548
DOI: 10.1126/sciadv.adw4402
Musavinezhad M., Shkarin A., Renger J., Utikal T., Götzinger S., Sandoghdar V.:
On-Chip Stark Tuning of Molecular Resonances in Nanoprinted Crystals
2025 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2025 (Munich, DEU, 23. June 2025 - 27. June 2025)
In: 2025 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2025 2025
DOI: 10.1109/CLEO/EUROPE-EQEC65582.2025.11109106
Nobakht J., Pscherer A., Renger J., Götzinger S., Sandoghdar V.:
Hybridization of molecules via a common photonic mode
In: Proceedings of the National Academy of Sciences of the United States of America 122 (2025), Article No.: e2505161122
ISSN: 0027-8424
DOI: 10.1073/pnas.2505161122
Pourtalebijahromi L., Kronast B., Munkert J., Sana L., Koch M., Danzer H., Dormeyer S., Jiang S., Herrmann F., Weiler M., Kashkanova A., Sandoghdar V., Zaiss M., Fuhrmann G.:
Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome
In: Small (2025)
ISSN: 1613-6829
DOI: 10.1002/smll.202502551
Sant V., Matthes D., Mazal H., Antonschmidt L., Wieser F., Movellan KT., Xue K., Nimerovsky E., Stampolaki M., Nathan M., Riedel D., Becker S., Sandoghdar V., de Groot BL., Griesinger C., Andreas LB.:
Lipidic folding pathway of α-Synuclein via a toxic oligomer
In: Nature Communications 16 (2025), p. 760-
ISSN: 2041-1723
DOI: 10.1038/s41467-025-55849-3
Tuna Y., Al-Hiyasat A., Kashkanova AD., Dechant A., Lutz E., Sandoghdar V.:
Electrostatic All-Passive Force Clamping of Charged Nanoparticles
In: ACS nano (2025)
ISSN: 1936-0851
DOI: 10.1021/acsnano.4c17299
Tuna Y., Sandoghdar V.:
Supported Lipid Bilayers as Stochastic Conveyor Belt for Delivery to the Near Field of Nanoscopic Structures
In: Journal of Physical Chemistry C 129 (2025), p. 495-499
ISSN: 1932-7447
DOI: 10.1021/acs.jpcc.4c06908
Zhang XC., Xue K., Salvi M., Schomburg B., Mehrens J., Giller K., Stopp M., Weisenburger S., Böning D., Sandoghdar V., Unden G., Becker S., Andreas LB., Griesinger C.:
Mechanism of sensor kinase CitA transmembrane signaling
In: Nature Communications 16 (2025), Article No.: 935
ISSN: 2041-1723
DOI: 10.1038/s41467-024-55671-3

Holler C., Taylor RW., Schambony A., Möckl L., Sandoghdar V.:
A paintbrush for delivery of nanoparticles and molecules to live cells with precise spatiotemporal control
In: Nature methods (2024)
ISSN: 1548-7105
DOI: 10.1038/s41592-024-02177-x
Kasaian K., Mazaheri M., Sandoghdar V.:
Long-Range Three-Dimensional Tracking of Nanoparticles Using Interferometric Scattering Microscopy
In: ACS nano (2024)
ISSN: 1936-0851
DOI: 10.1021/acsnano.4c08435
Kashkanova AD., Albrecht D., Küppers M., Blessing M., Sandoghdar V.:
Measuring Concentration of Nanoparticles in Polydisperse Mixtures Using Interferometric Nanoparticle Tracking Analysis
In: ACS nano (2024)
ISSN: 1936-0851
DOI: 10.1021/acsnano.4c04396
Mazaheri M., Kasaian K., Albrecht D., Renger J., Utikal T., Holler C., Sandoghdar V.:
iSCAT microscopy and particle tracking with tailored spatial coherence
In: Optica 11 (2024), p. 1030-1038
ISSN: 2334-2536
DOI: 10.1364/OPTICA.523788
Morales-Inostroza L., Folz J., Kühnemuth R., Felekyan S., Wieser FF., Seidel CA., Götzinger S., Sandoghdar V.:
An optofluidic antenna for enhancing the sensitivity of single-emitter measurements
In: Nature Communications 15 (2024), Article No.: 2545
ISSN: 2041-1723
DOI: 10.1038/s41467-024-46730-w
Musavinezhad M., Renger J., Zirkelbach J., Utikal T., Hail CU., Basché T., Poulikakos D., Götzinger S., Sandoghdar V.:
High-Resolution Cryogenic Spectroscopy of Single Molecules in Nanoprinted Crystals
In: ACS nano (2024)
ISSN: 1936-0851
DOI: 10.1021/acsnano.4c02003
Sandoghdar V.:
Essay: Exploring the Physics of Basic Medical Research
In: Physical Review Letters 132 (2024), Article No.: 090001
ISSN: 0031-9007
DOI: 10.1103/PhysRevLett.132.090001

Dahmardeh M., Dastjerdi HM., Mazal H., Köstler H., Sandoghdar V.:
Breaking new ground in protein detection: Self-supervised machine learning and iSCAT enable label-free detection of single proteins below 10 kDa
Biophotonics Congress: Optics in the Life Sciences 2023, OMA, NTM, BODA, OMP, BRAIN 2023 - Part of Optica Biophotonics Congress: Optics in the Life Sciences (Vancouver, BC, CAN, 24. April 2023 - 27. April 2023)
In: Bio-Optics: Design and Application in Proceedings Biophotonics Congress: Optics in the Life Sciences 2023, OMA, NTM, BODA, OMP, BRAIN 2023 2023
DOI: 10.1364/BODA.2023.JW2A.3
Dahmardeh M., Mirzaalian Dastjerdi H., Mazal H., Köstler H., Sandoghdar V.:
Self-supervised machine learning pushes the sensitivity limit in label-free detection of single proteins below 10 kDa
In: Nature methods (2023)
ISSN: 1548-7105
DOI: 10.1038/s41592-023-01778-2
Kashkanova AD., Blessing M., Reischke M., Baur JO., Baur A., Sandoghdar V., Van Deun J.:
Label-free discrimination of extracellular vesicles from large lipoproteins.
In: Journal of Extracellular Vesicles 12 (2023)
ISSN: 2001-3078
DOI: 10.1002/jev2.12348
Küppers M., Albrecht D., Kashkanova AD., Lühr J., Sandoghdar V.:
Confocal interferometric scattering microscopy reveals 3D nanoscopic structure and dynamics in live cells
In: Nature Communications 14 (2023), p. 1962-
ISSN: 2041-1723
DOI: 10.1038/s41467-023-37497-7
Mazal H., Wieser FF., Sandoghdar V.:
Insights into protein structure using cryogenic light microscopy
In: Biochemical Society Transactions 51 (2023), p. 2041-2059
ISSN: 0300-5127
DOI: 10.1042/BST20221246
Musavinezhad M., Shkarin A., Rattenbacher D., Renger J., Utikal T., Götzinger S., Sandoghdar V.:
Quantum Efficiency of Single Dibenzoterrylene Molecules in p-Dichlorobenzene at Cryogenic Temperatures
In: Journal of Physical Chemistry B 127 (2023), p. 5353-5359
ISSN: 1520-6106
DOI: 10.1021/acs.jpcb.3c01755
Rattenbacher D., Shkarin A., Renger J., Utikal T., Gotzinger S., Sandoghdar V.:
On-chip interference of scattering from two individual molecules
In: Optica 10 (2023), p. 1595-1601
ISSN: 2334-2536
DOI: 10.1364/OPTICA.502221
Zirkelbach J., Gurlek B., Mirzaei M., Shkarin A., Utikal T., Götzinger S., Sandoghdar V.:
Spectral splitting of a stimulated Raman transition in a single molecule
In: Physical Review Research 5 (2023), Article No.: 043244
ISSN: 2643-1564
DOI: 10.1103/PhysRevResearch.5.043244

Blessing M., Kashkanova AD., Gemeinhardt A., Sandoghdar V.:
Next-generation particle sizing: interferometric nanoparticle tracking analysis (iNTA)
Optical Sensors, Sensors 2022 (Vancouver, BC, CAN, 11. July 2022 - 15. July 2022)
In: Optics InfoBase Conference Papers 2022
Gurlek B., Sandoghdar V., Martin-Cano D.:
Engineering long-lived vibrational states for an organic molecule
12th International Conference on Metamaterials, Photonic Crystals and Plasmonics, META 2022 (Torremolinos, 19. July 2022 - 22. July 2022)
In: Said Zouhdi (ed.): International Conference on Metamaterials, Photonic Crystals and Plasmonics 2022
Kashkanova AD., Blessing M., Gemeinhardt A., Soulat D., Sandoghdar V.:
Precision size and refractive index analysis of weakly scattering nanoparticles in polydispersions
In: Nature Methods (2022)
ISSN: 1548-7091
DOI: 10.1038/s41592-022-01460-z
Küppers M., Albrecht D., Kashkanova A., Lühr J., Sandoghdar V.:
Nanoscale Imaging of Live Cells with Confocal Interferometric Scattering Microscopy (iSCAT)
Microscopy Histopathology and Analytics, Microscopy 2022 (Fort Lauderdale, FL, USA, 24. April 2022 - 27. April 2022)
In: Optics InfoBase Conference Papers 2022
Liu HW., Becker MA., Matsuzaki K., Kumar R., Götzinger S., Sandoghdar V.:
Robust Tipless Positioning Device for Near-Field Investigations: Press and Roll Scan (PROscan)
In: ACS nano (2022)
ISSN: 1936-0851
DOI: 10.1021/acsnano.2c05047
Mazaheri M., Kasaian K., Sandoghdar V.:
Long-Range High-Speed 3D Tracking via Interferometric Scattering Microscopy
Clinical and Translational Biophotonics, Translational 2022 (Fort Lauderdale, FL, USA, 24. April 2022 - 27. April 2022)
In: Optics InfoBase Conference Papers 2022
Mazal H., Wieser FF., Sandoghdar V.:
Deciphering a hexameric protein complex with Angstrom optical resolution
In: eLife 11 (2022)
ISSN: 2050-084X
DOI: 10.7554/eLife.76308
Mirzaalian Dastjerdi H., Dahmardeh M., Gemeinhardt A., Mahmoodabadi RG., Köstler H., Sandoghdar V.:
Optimized analysis for sensitive detection and analysis of single proteins via interferometric scattering microscopy
In: Journal of Physics D: Applied Physics 55 (2022)
ISSN: 0022-3727
DOI: 10.1088/1361-6463/ac2f68
Zirkelbach J., Mirzaei M., Deperasińska I., Kozankiewicz B., Gurlek B., Shkarin A., Utikal T., Götzinger S., Sandoghdar V.:
High-resolution vibronic spectroscopy of a single molecule embedded in a crystal
In: Journal of Chemical Physics 156 (2022), Article No.: 104301
ISSN: 0021-9606
DOI: 10.1063/5.0081297

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